drugset / Trial / NCT00060450

Inhaled Nitric Oxide in Prevention/Treatment of Ischemia-Reperfusion Lung Injury Related to Lung Transplantation

NCT00060450

Phase 3 Terminated 84 enrolled Mallinckrodt
RandomizedParallel-groupTriple-blindPrevention

Summary

The purpose of this study is to evaluate the effects of inhaled nitric oxide on both short-term physiology as well as on the development of ischemia-reperfusion lung injury (IRLI) in the immediate post transplant period. The specific hypothesis is that inhaled NO post lung transplantation will improve gas exchange/hemodynamic and thus reduce the development of post transplant IRLI.

Timeline

Start
2001-08
Primary completion
2006-09
Completion
2006-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Nitric Oxide Other / unclassified 10 ppm Inhaled
Subject Nitric Oxide Other / unclassified 20 ppm Inhaled

Indications