drugset / Trial / NCT00060567
Dose-Finding Study of E7070 in Combination With Irinotecan
Non-randomizedSingle-groupOpen-labelTreatment
Summary
E7070 and irinotecan will be administered to patients with GI tract, pancreatic or lung tumors on Days 1 and 8 of a 21-day cycle, or Days 1 and 15 of a 28-day cycle according to one of two E7070 dose escalation schemes.
Timeline
- Start
- 2003-03
- Primary completion
- 2013-03
- Completion
- 2013-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Irinotecan | Small molecule | 100 mg/m2 | — |
| Subject | Irinotecan | Small molecule | 125 mg/m2 | — |
| Subject | indisulam | Small molecule | 250 mg/m2 | — |
| Subject | indisulam | Small molecule | 400 mg/m2 | — |