drugset / Trial / NCT00060671

Comparative Trial for Pixantrone in Combination With Rituximab in Indolent Non-Hodgkin's Lymphoma

NCT00060671

Phase 3 Terminated 800 enrolled CTI BioPharma
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to determine whether combining pixantrone (BBR 2778, INN name pending) with the monoclonal antibody rituximab, leads to an increase in the period of patients' remission, compared to rituximab alone.

Timeline

Start
2005-01
Primary completion
2006-01
Completion
2006-01

Publications

  • Results Santoro A; Voglova J; Gabrail N; Ciuleanu T; Liberati M; Hancock BW; Stromatt S; Caballero D; Comparative Trial of Pixantrone + Rituximab vs Single agent Rituximab in the Treatment of Relapsed/Refractory Indolent Non-Hodgkin's Lymphoma; American Society of Clinical Oncology abstract and poster; Part 1, Vol 24 No 18S, June 20 supplement, 2006: 7578

Drugs

EvaluationDrugModalityDoseRoute
Subject Pixantrone Small molecule
Background Rituximab Monoclonal antibody

Indications