Irinotecan and Thalidomide in Treating Patients With Advanced Solid Tumors

Summary

Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. Drugs used in chemotherapy such as irinotecan use different ways to stop tumor cells from dividing so they stop growing or die. Combining thalidomide with irinotecan may kill more tumor cells. This randomized phase I trial is studying the side effects and best way to give irinotecan and thalidomide in treating patients with metastatic or unresectable solid tumors

Timeline

Start

2003-04

Primary completion

2006-05

Completion

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Drugs

Indications