3-AP and Gemcitabine in Treating Patients With Unresectable or Metastatic Pancreatic Cancer

Summary

RATIONALE: Drugs used in chemotherapy such as gemcitabine use different ways to stop tumor cells from dividing so they stop growing or die. 3-AP may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth and may help gemcitabine kill more cancer cells by making them more sensitive to the drug. PURPOSE: This phase II trial is studying how well giving gemcitabine together with 3-AP works in treating patients with unresectable or metastatic pancreatic cancer.

Timeline

Start

2003-01

Primary completion

2006-08

Completion

2008-08

Drugs

Indications