Sertraline Compared With Hypericum Perforatum (St.John's Wort) in Treating Depression

Summary

RATIONALE: Antidepressants such as sertraline and the herb hypericum perforatum (St. John's wort) may be effective in treating mild to moderate depression. It is not yet known which treatment is more effective in improving depression in patients who have cancer. PURPOSE: This randomized phase III trial is studying how well sertraline works compared to St. John's wort in treating mild to moderate depression in patients with solid tumors.

Timeline

Start

2004-03-01

Primary completion

2005-04-01

Completion

2005-11-01

Drugs

Indications