Yakima Head Start Fluoride Varnish Study

Phase 3 Completed 500 enrolled University of Washington Enterprise for Progress in the Community · collab National Institute of Dental and Craniofacial Research (NIDCR) · collab The Yakima Valley Farm Workers Clinic · collab Washington State Migrant Council · collab

RandomizedParallel-groupDouble-blindTreatment

Summary

The aim of this study is to determine whether an annual application of three (3) fluoride varnish doses over two weeks is at least as effective in reducing cavities as the current semi-annual application.

Timeline

Start: 2003-11
Primary completion: 2005-07
Completion: 2005-08

Outcome

Missed primary endpoint

paper equivalence of the treatments cannot be concluded. PMID 20016179 ↗

Publications

Weinstein P, Spiekerman C, Milgrom P. Randomized equivalence trial of intensive and semiannual applications of fluoride varnish in the primary dentition. Caries Res. 2009;43(6):484-90. doi: 10.1159/000264686. Epub 2009 Dec 10.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	NaF	Unknown	0.3 ml	Topical
Subject	NaF	Unknown	50 mg/ml	Topical