drugset / Trial / NCT00069927
Adderall XR Compared With Concerta in Treating Young Cancer Patients With Memory, Attention, and Depression
RandomizedCrossoverOpen-labelSupportive care
Summary
RATIONALE: Stimulant drugs such as dextroamphetamine-amphetamine and methylphenidate may help improve memory, attention, and thinking problems caused by central nervous system (CNS) treatment for cancer, and may help decrease depression. PURPOSE: This randomized phase II trial is studying dextroamphetamine-amphetamine to see how well it works compared to methylphenidate in treating depression and problems with memory, attention, and thinking in children who have undergone CNS treatment for cancer. This trial will also study how often depression is seen and if these medications might help.
Timeline
- Start
- 2003-08
- Primary completion
- 2006-06
- Completion
- 2006-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methylphenidate | Small molecule | 10 mg | Oral |
| Subject | Methylphenidate | Small molecule | 18 mg | Oral |