Temozolomide and Thalidomide in Treating Patients With Brain Metastases Secondary to Melanoma

Summary

This phase II trial is studying how well giving temozolomide together with thalidomide works in treating patients with brain metastases secondary to melanoma. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop tumor cells from dividing so they stop growing or die. Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. Combining temozolomide with thalidomide may kill more tumor cells

Timeline

Start

2003-10

Primary completion

2006-09

Completion

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Drugs

Indications