drugset / Trial / NCT00073957

Y 90 Ibritumomab Tiuxetan &Rituximab Relapsed or Refractory Diffuse Large B-Cell Non-Hodgkin's Lymphoma

NCT00073957 ↗

Phase 2 Completed 25 enrolled Beth Israel Deaconess Medical Center
NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Monoclonal antibodies, such as yttrium Y 90 ibritumomab tiuxetan and rituximab, can locate cancer cells and either kill them or deliver radioactive cancer-killing substances to them without harming normal cells. Combining yttrium Y 90 ibritumomab tiuxetan with rituximab may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combining yttrium Y 90 Ibritumomab tiuxetan with rituximab in treating patients who have relapsed or refractory diffuse large B-cell non-Hodgkin's lymphoma.

Timeline

Start
2003-12
Primary completion
2012-01-01
Completion
2012-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Rituximab Monoclonal antibody — Intravenous
Background Cytarabine Small molecule — Intrathecal

Indications