drugset / Trial / NCT00075673

Vinorelbine and Celecoxib in Treating Women With Relapsed or Metastatic Breast Cancer

NCT00075673

Phase 1 Terminated 6 enrolled Case Comprehensive Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Celecoxib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. Drugs used in chemotherapy, such as vinorelbine, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining vinorelbine with celecoxib may kill more tumor cells. PURPOSE: Phase I trial to determine the effectiveness of combining vinorelbine with celecoxib in treating women who have relapsed or metastatic breast cancer.

Timeline

Start
2003-11
Primary completion
2004-09
Completion
2005-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Celecoxib Other / unclassified Oral
Subject Vinorelbine Small molecule Oral

Indications