drugset / Trial / NCT00075673
Vinorelbine and Celecoxib in Treating Women With Relapsed or Metastatic Breast Cancer
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: Celecoxib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth. Drugs used in chemotherapy, such as vinorelbine, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining vinorelbine with celecoxib may kill more tumor cells. PURPOSE: Phase I trial to determine the effectiveness of combining vinorelbine with celecoxib in treating women who have relapsed or metastatic breast cancer.
Timeline
- Start
- 2003-11
- Primary completion
- 2004-09
- Completion
- 2005-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Celecoxib | Other / unclassified | — | Oral |
| Subject | Vinorelbine | Small molecule | — | Oral |