Pharmacologic Treatment of PTSD in Sexually Abused Children

Phase 3 Completed 24 enrolled Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) National Institute of Mental Health (NIMH) · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study will evaluate the benefit of adding sertraline (Zoloft®) to Trauma-Focused Cognitive Behavioral Therapy (TF-CBT) for sexually abused children who have Posttraumatic Stress Disorder (PTSD).

Timeline

Start: 2001-04
Primary completion: 2006-03
Completion: 2006-03

Publications

Background Cohen JA, Mannarino AP, Perel JM, Staron V. A pilot randomized controlled trial of combined trauma-focused CBT and sertraline for childhood PTSD symptoms. J Am Acad Child Adolesc Psychiatry. 2007 Jul;46(7):811-9. doi: 10.1097/chi.0b013e3180547105.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sertraline	Small molecule	50 mg	Oral
Subject	Sertraline	Small molecule	150 mg	Oral

Pharmacologic Treatment of PTSD in Sexually Abused Children

Summary

Timeline

Publications

Drugs

Indications