Amino Acid Therapy for Hot Flashes in Postmenopausal Women

NCT00081952 ↗

Phase 1/2 Completed 15 enrolled National Center for Complementary and Integrative Health (NCCIH)

RandomizedParallel-groupTreatment

Summary

The purpose of this study is to determine the safety, tolerability, and effectiveness of the amino acid L-isoleucine in the treatment of hot flashes in postmenopausal women.

Timeline

Start: 2003-10
Primary completion: 2007-10
Completion: 2007-10

Publications

Guttuso T, McDermott MP, Su H, Kieburtz K. Effects of L-isoleucine and L-valine on hot flushes and serum homocysteine: a randomized controlled trial. Obstet Gynecol. 2008 Jul;112(1):109-15. doi: 10.1097/AOG.0b013e31817d53b6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Background	L-norleucine	Unknown	—	—

Indications

No indication recorded.