Irinotecan and 3-AP in Treating Patients With Metastatic or Unresectable Solid Tumors

Summary

This phase I trial is studying the side effects and best dose of irinotecan and 3-AP in treating patients with metastatic or unresectable solid tumors. Drugs used in chemotherapy such as irinotecan work in different ways to stop tumor cells from dividing so they stop growing or die. 3-AP may stop the growth of tumor cells by blocking the enzymes necessary for their growth and may help irinotecan kill more tumor cells by making them more sensitive to the drug.

Timeline

Start

2004-03

Primary completion

2008-07

Completion

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Drugs

Indications