Study of AMG 706 in Subjects With Advanced Gastrointestinal Stromal Tumors (GISTs)

Summary

This study will determine the safety and effectiveness of AMG 706 in patients with advanced GIST.

Timeline

Start

2004-10

Primary completion

2006-06

Completion

2008-06

Publications

• Results Benjamin RS, Schoffski P, Hartmann JT, Van Oosterom A, Bui BN, Duyster J, Schuetze S, Blay JY, Reichardt P, Rosen LS, Skubitz K, McCoy S, Sun YN, Stepan DE, Baker L. Efficacy and safety of motesanib, an oral inhibitor of VEGF, PDGF, and Kit receptors, in patients with imatinib-resistant gastrointestinal stromal tumors. Cancer Chemother Pharmacol. 2011 Jul;68(1):69-77. doi: 10.1007/s00280-010-1431-9. Epub 2010 Sep 14.

Drugs

Indications