The Safety and Efficacy of Neramexane in Patients With Moderate to Severe Alzheimer's Disease

Summary

Memory loss and difficulties with thinking associated with Alzheimer's disease may be due to chronic release of a brain chemical called glutamate. Glutamate helps transmit messages between nerve cells through interaction with a certain type of receptor (N-methyl-D-aspartate, NMDA) on the cell. Neramexane is a new drug that blocks the effects of excessive glutamate at the receptor (NMDA receptor antagonist).

Timeline

Start

2003-03

Primary completion

2005-03

Completion

2005-03

Drugs

Indications