drugset / Trial / NCT00091078

Oblimersen and Imatinib Mesylate in Treating Patients With Advanced Gastrointestinal Stromal Tumors That Cannot Be Removed By Surgery

NCT00091078

Phase 2 Terminated 96 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

Imatinib mesylate may stop the growth of tumor cells by blocking the enzymes necessary for their growth. Oblimersen may help imatinib mesylate kill more tumor cells by making tumor cells more sensitive to the drug. This phase II trial is studying how well giving imatinib mesylate together with oblimersen works in treating patients with advanced gastrointestinal stromal tumor that cannot be removed by surgery.

Timeline

Start
2005-09
Primary completion
2006-07
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Imatinib Small molecule Oral
Subject oblimersen sodium Antisense oligonucleotide Intravenous