drugset / Trial / NCT00093522
Vaccine Therapy With or Without Fludarabine in Treating Patients With Stage IV Kidney Cancer
RandomizedTreatment
Summary
RATIONALE: Vaccines made from a person's tumor cells and white blood cells may make the body build an immune response to kill tumor cells. Drugs used in chemotherapy, such as fludarabine, work in different ways to stop tumor cells from dividing so they stop growing or die. Combining vaccine therapy with fludarabine may kill more tumor cells. PURPOSE: This randomized phase II trial is studying vaccine therapy and fludarabine to see how well they work compared to vaccine therapy alone in treating patients with stage IV kidney cancer.
Timeline
- Start
- 2004-08
- Primary completion
- —
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fludarabine | Small molecule | — | Intravenous |
| Subject | autologous tumor cell vaccine | Vaccine | — | — |
| Subject | therapeutic autologous dendritic cells | Vaccine | — | — |
| Background | keyhole limpet hemocyanin | Vaccine | — | — |