drugset / Trial / NCT00094367

A Study Comparing Safety Of Abacavir And Lamivudine Administered Once-Daily As A Single Tablet Versus The Same Drugs Administered Twice-Daily As Separate Tablets (ALOHA Study)

NCT00094367

Phase 3 Completed 900 enrolled GlaxoSmithKline
RandomizedParallel-groupOpen-labelTreatment

Summary

This study was designed to evaluate if subjects who took 600 mg of abacavir and 300 mg of lamivudine once-daily as a single tablet were just as likely to have adverse events compared to subjects who took 300 mg of abacavir and 150 mg of lamivudine administered as separate tablets twice-daily.

Timeline

Start
2004-07
Primary completion
2005-10
Completion
2005-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Abacavir Other / unclassified 300 mg
Subject Abacavir Other / unclassified 600 mg
Subject Lamivudine Other / unclassified 150 mg
Subject Lamivudine Other / unclassified 300 mg