drugset / Trial / NCT00098501

CCI-779 and EKB-569 in Treating Patients With Advanced Solid Tumors

NCT00098501

Phase 1 Completed 42 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase I trial is studying the side effects, best way to give, and best dose of CCI-779 and EKB-569 in treating patients with advanced solid tumors. Drugs used in chemotherapy, such as CCI-779, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. EKB-569 may stop the growth of tumor cells by blocking some of the enzymes needed for their growth. Giving CCI-779 together with EKB-569 may kill more tumor cells.

Timeline

Start
2004-10
Primary completion
2007-10
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Temsirolimus Small molecule Oral
Subject pelitinib Small molecule Oral