Celecoxib in Preventing Multiple Myeloma in Patients With Monoclonal Gammopathy or Smoldering Myeloma

Summary

This randomized phase II trial studies how well celecoxib works in preventing multiple myeloma in patients with monoclonal gammopathy or smoldering myeloma. Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of celecoxib may be effective in preventing multiple myeloma.

Timeline

Start

2004-11

Primary completion

2008-06

Completion

2008-11

Outcome

Missed primary endpoint

registry analysis (superiority or other test); Arm I (Celecoxib) vs Arm II (Placebo); p = .23; Median Difference (Final Values) .05; SAS version 8 NCT00099047 ↗

Drugs

Indications