Tipifarnib and Gemcitabine Hydrochloride in Treating Women With Metastatic Breast Cancer

Summary

This phase I/II trial is studying the side effects and best dose of tipifarnib when given together with gemcitabine hydrochloride and to see how well they work in treating women with breast cancer that has spread to other parts of the body. Tipifarnib is a drug that binds to specific proteins on the tumor cells and then kills these cells. Gemcitabine hydrochloride is a chemotherapy drug that may kill tumor cells by preventing cells from dividing. Giving tipifarnib together with gemcitabine hydrochloride may kill more tumor cells.

Timeline

Start

2005-09

Primary completion

2007-10

Completion

2010-01

Drugs

Indications