drugset / Trial / NCT00105313

Study to Evaluate MEDI-507 in Patients With CD2-Positive Lymphoma/Leukemia

NCT00105313

Phase 1 Terminated 80 enrolled MedImmune LLC
Non-randomizedSingle-groupOpen-labelTreatment

Summary

For primary objectives, we will determine the MTD and examine clinical responses and immune cell populations to determine an OBD, and describe the safety and tolerability of MEDI-507. For the secondary objectives we will look at the antitumor activity of MEDI 507, PK, serum concentrations, and immunogenicity of MEDI-507, as well as time courses of depletion and recovery of CD2 positive and total T-Cell populations.

Timeline

Start
2005-02
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Siplizumab Monoclonal antibody

Indications