drugset / Trial / NCT00108108

Dose-finding Trial of HCD122 in Patients With Chronic Lymphocytic Leukemia (CLL) That is Relapsed or Non-responsive to Prior Fludaribine Therapy

NCT00108108 ↗

Phase 1 Terminated 26 enrolled Novartis Pharmaceuticals XOMA (US) LLC · collab
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine the highest tolerated dose, safety and activity of HCD122 in patients with chronic lymphocytic leukemia who are relapsed after receiving prior treatment.

Timeline

Start
2005-04
Primary completion
2008-06
Completion
2008-06

Outcome

Outcome not reported

Stopped (Enrollment): “Slow enrollment and minimal preliminary biological and clinical efficacy.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Lucatumumab Monoclonal antibody — Intravenous