drugset / Trial / NCT00108121

Study to Determine the Safety of Two Applications of PEP005 Topical Gel to Nodular Basal Cell Carcinoma

NCT00108121

Phase 2 Completed 60 enrolled Peplin
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to determine whether topical application of PEP005 is safe for the treatment of nodular basal cell carcinoma.

Timeline

Start
2005-03
Primary completion
2006-05
Completion
2006-05

Publications

  • Results Rosen RH, Katsamas J, Ogbourne SM, Welburn P. Early phase clinical development of PEP005 topical gel for basal cell carcinoma. 21st World Congress of Dermatology, Buenos Aires, 2007. 2007: Poster no. P5755 (1 p.)
  • Results Rosen RH, Freeman M, Siller G, Katsamas J, Ogbourne SM. Safety and efficacy of PEP005 Topical Gel for the treatment of nodular and superficial forms of basal cell carcinoma. Summer Academy, American Academy of Dermatology meeting, New York, NY, 2007. 2007: Poster no. P1502

Drugs

EvaluationDrugModalityDoseRoute
Subject ingenol mebutate Small molecule 0.0025 % Topical
Subject ingenol mebutate Small molecule 0.01 % Topical
Subject ingenol mebutate Small molecule 0.05 % Topical

Indications