drugset / Trial / NCT00110552
Effects of Sage on Memory and Mental Performance in Alzheimer's Disease Patients
Phase 1
Completed
111 enrolled
Oregon Health and Science University
National Center for Complementary and Integrative Health (NCCIH) · collab
RandomizedParallel-groupSingle-blindTreatment
Summary
The purpose of this study is to determine the effectiveness of the herb sage in improving the mental function of individuals with Alzheimer's disease. Study hypothesis: The administration of sage will improve cognitive function in patients with mild Alzheimer's disease.
Timeline
- Start
- 2005-07
- Primary completion
- 2012-12
- Completion
- 2014-10
Publications
- Background Akhondzadeh S, Noroozian M, Mohammadi M, Ohadinia S, Jamshidi AH, Khani M. Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomized and placebo-controlled trial. J Clin Pharm Ther. 2003 Feb;28(1):53-9. doi: 10.1046/j.1365-2710.2003.00463.x.
- Background Perry NS, Bollen C, Perry EK, Ballard C. Salvia for dementia therapy: review of pharmacological activity and pilot tolerability clinical trial. Pharmacol Biochem Behav. 2003 Jun;75(3):651-9. doi: 10.1016/s0091-3057(03)00108-4.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Salvia officinalis | Unknown | — | Oral |