drugset / Trial / NCT00112034

AVONEX® Combination Trial - "ACT"

NCT00112034

Phase 4 Completed 350 enrolled Biogen
RandomizedFactorialDouble-blind

Summary

The purpose of this study is to determine the efficacy and safety of combination therapy with AVONEX plus low dose oral methotrexate (MTX), every other month courses of intravenous methylprednisolone (IVMP), or both in patients with continued disease activity on AVONEX monotherapy.

Timeline

Start
2003-06
Primary completion
2006-06
Completion
2007-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Methotrexate Small molecule Oral
Subject Methylprednisolone Other / unclassified Intravenous