drugset / Trial / NCT00112983

Eculizumab in Treating Patients With Paroxysmal Nocturnal Hemoglobinuria

NCT00112983

RandomizedDouble-blindPrevention

Summary

RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of eculizumab may prevent leukemia and stop the destruction of red blood cells in patients with paroxysmal nocturnal hemoglobinuria. PURPOSE: This randomized phase III trial is studying how well eculizumab works in treating patients with paroxysmal nocturnal hemoglobinuria.

Timeline

Start
2004-11
Primary completion
Completion
2005-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Eculizumab Monoclonal antibody Intravenous

Indications