drugset / Trial / NCT00115661
Use of Rosiglitazone in the Treatment of Endometriosis
Phase 2
Terminated
25 enrolled
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Berlex Foundation · collab
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to perform a pilot study on the efficacy of rosiglitazone in reducing pelvic pain in early stage endometriosis patients.
Timeline
- Start
- 2005-07
- Primary completion
- 2006-05
- Completion
- 2006-05
Publications
- Background Lebovic DI, Kir M, Casey CL. Peroxisome proliferator-activated receptor-gamma induces regression of endometrial explants in a rat model of endometriosis. Fertil Steril. 2004 Oct;82 Suppl 3:1008-13. doi: 10.1016/j.fertnstert.2004.02.148.
- Moravek MB, Ward EA, Lebovic DI. Thiazolidinediones as therapy for endometriosis: a case series. Gynecol Obstet Invest. 2009;68(3):167-70. doi: 10.1159/000230713. Epub 2009 Jul 30.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rosiglitazone | Small molecule | 4 mg | — |