drugset / Trial / NCT00117533

Pegylated Interferon Alfa-2b Plus Ribavirin in Chronic Hepatitis B and Delta

NCT00117533

Non-randomizedSingle-groupOpen-labelTreatment

Summary

The treatment of choice for chronic hepatitis D is uncertain. The investigators hypothesize that pegylated interferon (IFN) alfa-2b in combination with ribavirin (RBV) may be effective in the treatment of chronic hepatitis D patients who are also infected by hepatitis B virus (HBV). The purpose of this study is to test this hypothesis. The investigators will use pegylated IFN alfa-2b in combination with RBV for the treatment of patients with dual chronic hepatitis D virus (HDV) and HBV infection. A 24-week course of combination therapy pegylated IFN+RBV will be used.

Timeline

Start
2005-09
Primary completion
Completion
2007-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Ribavirin Small molecule 1000 mg
Subject Ribavirin Small molecule 1200 mg
Subject pegylated IFN alfa-2b Unknown