Therapies for Treatment-Resistant Panic Disorder Symptoms

Phase 2/3 Completed 46 enrolled Massachusetts General Hospital National Institute of Mental Health (NIMH) · collab

RandomizedParallel-groupTriple-blindTreatment

Summary

This study will determine the effectiveness of different treatments for panic disorder symptoms in individuals who still have symptoms after initial treatment with medication.

Timeline

Start: 1999-03
Primary completion: 2007-10
Completion: 2007-10

Publications

Simon NM, Otto MW, Worthington JJ, Hoge EA, Thompson EH, Lebeau RT, Moshier SJ, Zalta AK, Pollack MH. Next-step strategies for panic disorder refractory to initial pharmacotherapy: a 3-phase randomized clinical trial. J Clin Psychiatry. 2009 Nov;70(11):1563-70. doi: 10.4088/JCP.08m04485blu. Epub 2009 Oct 6.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Clonazepam	Small molecule	—	—
Subject	Sertraline	Small molecule	100 mg	—
Subject	Sertraline	Small molecule	200 mg	—

Therapies for Treatment-Resistant Panic Disorder Symptoms

Summary

Timeline

Publications

Drugs

Indications