drugset / Trial / NCT00125437

Larger Dose of Spironolactone for the Treatment of Patients With Nonischemic Cardiomyopathy

NCT00125437

Terminated 200 enrolled Hebei Medical University
RandomizedParallel-groupSingle-blindTreatment

Summary

The purpose of this study is to determine whether a larger dose of the aldosterone antagonist spironolactone combined with a lower dose of an ACE inhibitor is more effective in reverse left ventricular remodeling in severe congestive heart failure in patients with nonischemic cardiomyopathy.

Timeline

Start
2005-09
Primary completion
Completion
2009-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Spironolactone Small molecule