drugset / Trial / NCT00125515
Memantine and Naltrexone Treatment for Opioid Dependence
Phase 2
Completed
81 enrolled
New York State Psychiatric Institute
National Institute on Drug Abuse (NIDA) · collab
RandomizedParallel-groupTriple-blindTreatment
Summary
The goal of this study is to test the efficacy of memantine (a noncompetitive NMDA receptor antagonist) as an adjunct to the maintenance treatment with naltrexone in detoxified heroin-dependent individuals.
Timeline
- Start
- 2005-06
- Primary completion
- 2008-08
- Completion
- 2008-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Memantine | Unknown | 15 mg | — |
| Comparator | Memantine | Unknown | 30 mg | — |
| Comparator | Naltrexone | Small molecule | 50 mg | Oral |