D-cycloserine in the Management of Chronic Low Back Pain

Summary

Pre-clinical studies in rats suggest that D-cycloserine (DCS) is effective in the management of chronic neuropathic pain. This pilot study will attempt to determine the effect of D-cycloserine in the treatment of chronic low back pain. Other aims of this study are to determine the safety of D-cycloserine in the treatment of chronic low back pain and to determine which pain measurement scales are best at measuring the efficacy of treatment.

Timeline

Start

2012-07

Primary completion

2014-04

Completion

2014-11

Publications

• Results Schnitzer TJ, Torbey S, Herrmann K, Kaushal G, Yeasted R, Vania Apkarian A. A randomized placebo-controlled pilot study of the efficacy and safety of D-cycloserine in people with chronic back pain. Mol Pain. 2016 Nov 15;12:1744806916678627. doi: 10.1177/1744806916678627. Print 2016.

Drugs

Indications

No indication recorded.