drugset / Trial / NCT00125957

The Effects of Wellbutrin (Bupropion) on Residual and Cognitive Symptoms in SSRI-treated Depression

NCT00125957

RandomizedCrossoverTriple-blindTreatment

Summary

Many people with depression are treated with a serotonin-specific reuptake inhibitor anti-depressant (SSRI) and feel 'better'. Although many people feel 'better', they do not feel completely 'well'. Often, individuals continue to complain of cognitive problems such as lack of attention, diminished motivation, and impaired problem-solving. This study looks at whether residual and cognitive symptoms of depression in individuals are affected by the addition of Wellbutrin (bupropion).

Timeline

Start
2005-08
Primary completion
2010-01
Completion
2011-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupropion Small molecule 100 mg
Subject Bupropion Small molecule 150 mg