drugset / Trial / NCT00126282

A Medication Trial Combined With Behavior Therapy for Individuals With Obsessive-compulsive Disorder

NCT00126282

Completed 50 enrolled Massachusetts General Hospital
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study examines the efficacy of the medication D-Cycloserine in the reduction of obsessions and compulsions in individuals with obsessive-compulsive disorder (OCD). All study participants will receive Exposure and Response Prevention, a common form of behavior therapy for individuals with OCD. Half (50%) of the participants will be randomly assigned to the placebo condition and the other half (50%) will be randomly assigned to receive D-Cycloserine. Because all participants will receive 10 sessions of behavior therapy, all participants are expected to improve from this treatment.

Timeline

Start
2003-12
Primary completion
Completion
2007-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Cycloserine Small molecule