Safety and Immunogenicity of a New Formulation of a Bivalent Killed, Whole-Cell Oral Cholera Vaccine

Phase 2 Completed 150 enrolled International Vaccine Institute Göteborg University · collab National Institute of Hygiene and Epidemiology, Vietnam · collab

RandomizedSingle-groupDouble-blindPrevention

Summary

The purpose of this study is to evaluate the safety and immunogenicity of a new formulation of a locally-produced bivalent, (O-1 and O-139) killed whole cell oral cholera vaccine among Vietnamese adults.

Timeline

Start: 2005-05
Primary completion: —
Completion: 2005-06

Publications

Results Anh DD, Canh DG, Lopez AL, Thiem VD, Long PT, Son NH, Deen J, von Seidlein L, Carbis R, Han SH, Shin SH, Attridge S, Holmgren J, Clemens J. Safety and immunogenicity of a reformulated Vietnamese bivalent killed, whole-cell, oral cholera vaccine in adults. Vaccine. 2007 Jan 22;25(6):1149-55. doi: 10.1016/j.vaccine.2006.09.049. Epub 2006 Sep 29.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	killed oral cholera vaccine	Vaccine	—	Oral

Safety and Immunogenicity of a New Formulation of a Bivalent Killed, Whole-Cell Oral Cholera Vaccine

Summary

Timeline

Publications

Drugs

Indications