drugset / Trial / NCT00129246
Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain
Phase 1/2
Completed
40 enrolled
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA) · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
This study will test a combination of the drugs naltrexone and bupropion with weight-concerned smokers to investigate whether or not this combination of drugs improves smoking cessation quit rates and minimizes post quit weight gain.
Timeline
- Start
- 2004-12
- Primary completion
- —
- Completion
- 2005-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bupropion | Small molecule | 300 mg | — |
| Subject | Naltrexone | Small molecule | 25 mg | — |