drugset / Trial / NCT00130767

Kinetics of the Finasteride Prostate Induced Apoptosis

NCT00130767

Phase 4 Unknown 90 enrolled Hospices Civils de Lyon
RandomizedParallel-groupOpen-labelTreatment

Summary

The aim of this study is to evaluate the mechanisms involved in the apoptosis induced by a treatment of finasteride on benign prostate hyperplasia (BPH). Five sets of patients who need a surgical procedure because of low tract urinary symptoms are randomly attributed to one of five sets of treatment: 0, 7, 14, 21 or 28 days of finasteride treatment before the day of the procedure. Prostate histological fragments are conditioned for molecular and histologic studies.

Timeline

Start
2004-12
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Finasteride Small molecule