drugset / Trial / NCT00132821
Impact of Smoking Cessation on Sleep - 5
RandomizedFactorialTriple-blindTreatment
Summary
Smoking is a major health problem with a direct link to elevated heart- and lung-related problems. Nicotine is highly addictive, which makes quitting difficult and relapse after quitting highly probable. Any type of sleep disturbance may make quitting even harder. The purpose of this study is to evaluate the effect of bupropion and nicotine replacement therapies (NRT) on sleep disturbances. In turn, this might show how such medications affect attempts at smoking cessation.
Timeline
- Start
- 2005-08
- Primary completion
- 2009-05
- Completion
- 2009-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Bupropion | Small molecule | 300 mg | — |
| Comparator | Nicotine | Unknown | 21 mg | Other |