drugset / Trial / NCT00132821

Impact of Smoking Cessation on Sleep - 5

NCT00132821

Phase 4 Completed 59 enrolled National Institute on Drug Abuse (NIDA)
RandomizedFactorialTriple-blindTreatment

Summary

Smoking is a major health problem with a direct link to elevated heart- and lung-related problems. Nicotine is highly addictive, which makes quitting difficult and relapse after quitting highly probable. Any type of sleep disturbance may make quitting even harder. The purpose of this study is to evaluate the effect of bupropion and nicotine replacement therapies (NRT) on sleep disturbances. In turn, this might show how such medications affect attempts at smoking cessation.

Timeline

Start
2005-08
Primary completion
2009-05
Completion
2009-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bupropion Small molecule 300 mg
Comparator Nicotine Unknown 21 mg Other