drugset / Trial / NCT00142103

CPG10101 Combination Therapy For The Treatment Of Hepatitis C In Relapsed Hepatitis C Virus (HCV) Subjects

NCT00142103

Phase 1 Completed 91 enrolled Pfizer
RandomizedParallel-groupOpen-labelTreatment

Summary

1. To characterize the tolerability profile of subcutaneous (SC) CPG 10101 alone, with pegylated interferon, ribavirin or both pegylated interferon and ribavirin when administered weekly for twelve weeks in relapsed HCV positive subjects. 2. To assess the effect of subcutaneous (SC) CPG 10101 alone, with pegylated interferon, ribavirin or both pegylated interferon and ribavirin on serum Hepatitis C Virus (HCV) RNA concentrations

Timeline

Start
2005-09
Primary completion
2007-02
Completion
2007-02

Drugs

EvaluationDrugModalityDoseRoute
Subject CPG10101 Unknown 0.2 mg/kg Subcutaneous
Subject Peginterferon alfa-2b Protein / enzyme biologic 1.5 ug/kg Subcutaneous
Subject Ribavirin Small molecule 800 mg Oral
Subject Ribavirin Small molecule 1400 mg Oral