drugset / Trial / NCT00143572

Use of Hydroxyurea and Magnesium Pidolate for Treatment of Sickle Cell Disease

NCT00143572

Phase 1 Completed 16 enrolled St. Jude Children's Research Hospital
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to estimate the MTD of Mg pidolate in combination with HU in patients with sickle cell disease who have been on a therapeutic dose (15-30 mg/kg/day) of HU for at least 6 months.

Timeline

Start
2004-11
Primary completion
2008-01
Completion
2008-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Magnesium Pidolate Small molecule 0.6 meq
Background Hydroxyurea Other / unclassified

Indications