drugset / Trial / NCT00144469

A Study of Peginterferon Alfa-2a in Combination With Ribavirin in Patients With Chronic Hepatitis C

NCT00144469

Phase 3 Completed 300 enrolled Chugai Pharmaceutical
RandomizedParallel-groupDouble-blindTreatment

Summary

This study evaluated the efficacy and safety of the combination of peginterferon alfa-2a plus ribavirin in treatment-naïve patients with HCV genotype 1b infection, compared with peginterferon alfa-2a monotherapy. Additionally, the study evaluated the efficacy and safety of the combination of peginterferon alfa-2a plus ribavirin in patients with CHC who had failed to respond to previous conventional-interferon based therapy.

Timeline

Start
2002-05
Primary completion
Completion
2005-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Peginterferon alfa-2a Protein / enzyme biologic 180 ug Subcutaneous
Subject Ribavirin Small molecule 600 mg Oral
Subject Ribavirin Small molecule 1000 mg Oral