drugset

drugset / Trial / NCT00147875

Study of Prednisone, Vinblastine, Doxorubicin, and Gemcitabine in Elderly Patients With Advanced Stages Hodgkin's Lymphoma

NCT00147875 ↗

Phase 1/2 Completed 60 enrolled University of Cologne Eli Lilly and Company · collab German Hodgkin's Lymphoma Study Group · collab

Non-randomizedSingle-groupOpen-labelTreatment

Summary

The objectives of this study are to assess the feasibility and efficacy of a combination chemotherapy (PVAG) in elderly patients with advanced stages Hodgkin's lymphoma.

Timeline

Start: 2004-03
Primary completion: 2007-07
Completion: —

Publications

Boll B, Bredenfeld H, Gorgen H, Halbsguth T, Eich HT, Soekler M, Markova J, Keller U, Graeven U, Kremers S, Geissler M, Trenn G, Fuchs M, von Tresckow B, Eichenauer DA, Borchmann P, Engert A. Phase 2 study of PVAG (prednisone, vinblastine, doxorubicin, gemcitabine) in elderly patients with early unfavorable or advanced stage Hodgkin lymphoma. Blood. 2011 Dec 8;118(24):6292-8. doi: 10.1182/blood-2011-07-368167. Epub 2011 Sep 13.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Doxorubicin	Other / unclassified	—	—
Subject	Gemcitabine	Small molecule	—	—
Subject	Prednisone	Other / unclassified	—	—
Subject	Vinblastine	Small molecule	—	—

Indications