drugset / Trial / NCT00148291

Phase III Study of Docetaxel Vs Vinorelbine in Elderly Patients With Advanced Non-Small Cell Lung Cancer

NCT00148291

Phase 3 Completed 180 enrolled West Japan Thoracic Oncology Group
RandomizedParallel-groupOpen-labelTreatment

Summary

Vinorelbine is currently the standard treatment for elderly patients with advanced non-small cell lung cancer (NSCLC). Docetaxel has also shown promising results against elderly patients in phase II studies. We conducted a randomized phase III trial to evaluate whether docetaxel provided better overall survival than vinorelbine in elderly patients with advanced NSCLC.

Timeline

Start
1999-06
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Docetaxel Small molecule 60 mg/m2
Subject Vinorelbine Small molecule 25 mg/m2

Indications