Trial of Asthma Patient Education (TAPE)

Phase 4 Completed 600 enrolled American Lung Association Asthma Clinical Research Centers National Heart, Lung, and Blood Institute (NHLBI) · collab

RandomizedFactorialDouble-blind

Summary

The purpose of this research study is to investigate the way that educational approaches and presentation of a drug may affect the response to montelukast and placebo (an inactive medication) in subjects with asthma.

Timeline

Start: 2003-12
Primary completion: 2005-12
Completion: 2005-12

Outcome

Missed primary endpoint

paper Peak flow and other lung function measures were not improved in participants assigned to the enhanced message groups versus the neutral messages groups PMID 19632710 ↗

Publications

Gerald JK, Carr TF, Wei CY, Holbrook JT, Gerald LB. Albuterol Overuse: A Marker of Psychological Distress? J Allergy Clin Immunol Pract. 2015 Nov-Dec;3(6):957-62. doi: 10.1016/j.jaip.2015.06.021. Epub 2015 Sep 1.
Wise RA, Bartlett SJ, Brown ED, Castro M, Cohen R, Holbrook JT, Irvin CG, Rand CS, Sockrider MM, Sugar EA; American Lung Association Asthma Clinical Research Centers. Randomized trial of the effect of drug presentation on asthma outcomes: the American Lung Association Asthma Clinical Research Centers. J Allergy Clin Immunol. 2009 Sep;124(3):436-44, 444e1-8. doi: 10.1016/j.jaci.2009.05.041. Epub 2009 Jul 25.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Montelukast	Other / unclassified	—	—