Comparison of Vascular Effects After Therapy With Irbesartan and Atorvastatin.

Completed Technical University Dresden

RandomizedCrossoverDouble-blindTreatment

Summary

Vascular responses to angiotensin II and histamine are compared before and after 30 days of systemic treatment with either irbesartan 150 mg or atorvastatin 20 mg.

Timeline

Start: 2003-03
Primary completion: —
Completion: 2006-10

Publications

Schindler C, Guenther K, Hermann C, Ferrario CM, Schroeder C, Haufe S, Jordan J, Kirch W. Statin treatment in hypercholesterolemic men does not attenuate angiotensin II-induced venoconstriction. PLoS One. 2014 Sep 29;9(9):e103909. doi: 10.1371/journal.pone.0103909. eCollection 2014.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Atorvastatin	Small molecule	20 mg	Oral
Subject	Irbesartan	Small molecule	150 mg	Oral

Indications

No indication recorded.