Use of NovoSeven® in Active Variceal Bleeding

Phase 2 Completed 265 enrolled Novo Nordisk A/S

RandomizedParallel-groupDouble-blindTreatment

Summary

This trial is conducted in Asia and Europe. The trial is planned to investigate the effectiveness and safety of NovoSeven® in patients with advanced cirrhosis and active variceal bleeding.

Timeline

Start: 2004-04
Primary completion: 2006-08
Completion: 2006-08

Publications

Results Hsia CC, Chin-Yee IH, McAlister VC. Use of recombinant activated factor VII in patients without hemophilia: a meta-analysis of randomized control trials. Ann Surg. 2008 Jul;248(1):61-8. doi: 10.1097/SLA.0b013e318176c4ec.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	eptacog alfa (activated)	Protein / enzyme biologic	—	—

Use of NovoSeven® in Active Variceal Bleeding

Summary

Timeline

Publications

Drugs

Indications