drugset / Trial / NCT00155558
A Phase I Trial of HDFL48 in Recurrent or Metastatic Colorectal Cancers
Non-randomizedParallel-groupOpen-labelDiagnostic
Summary
To determine the maximum tolerated dose and dose limiting toxicity of 5-FU and leucovorin with novel 48-hour infusion schedule, and to collect toxicity profile at different dose level of 5-FU/LV 48-hour infusion.
Timeline
- Start
- 2001-03
- Primary completion
- —
- Completion
- 2005-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Leucovorin | Small molecule | — | — |
| Subject | fluorouracil | Small molecule | — | — |