drugset

drugset / Trial / NCT00157066

Effects of Vitamin D Supplementation on Antimycobacterial Immunity

NCT00157066 ↗

Completed 230 enrolled Barts & The London NHS Trust Department of Clinical Biochemistry, Homerton Hospital, London E9 6SR, UK · collab Environmental Health Department, London Borough of Newham, London E15 4SF, UK · collab Imperial College London · collab Newham Chest Clinic, London E7 8QP, UK · collab Northwick Park Hospital, Harrow, UK · collab University of Cape Town · collab Wellcome Trust · collab

RandomizedParallel-groupDouble-blind

Summary

The purpose of this study is to determine how vitamin D supplementation (ergocalciferol) affects the immune response to mycobacterial infection.

Timeline

Start: 2002-12
Primary completion: —
Completion: 2006-09

Publications

Martineau AR, Wilkinson RJ, Wilkinson KA, Newton SM, Kampmann B, Hall BM, Packe GE, Davidson RN, Eldridge SM, Maunsell ZJ, Rainbow SJ, Berry JL, Griffiths CJ. A single dose of vitamin D enhances immunity to mycobacteria. Am J Respir Crit Care Med. 2007 Jul 15;176(2):208-13. doi: 10.1164/rccm.200701-007OC. Epub 2007 Apr 26.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ergocalciferol	Small molecule	2.5 mg	Oral

Indications